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Is it safe? · medication

Is St. John's Wort Safe During Pregnancy?

Medically reviewed by Dr. Elena Vasquez, MD, FAAP, Board-certified pediatrician & medical reviewer· Last updated June 11, 2026

The verdict

Best to avoid

Is st. john's wort safe during pregnancy?

St. John's Wort should be avoided in pregnancy because its safety is not established, it can interact dangerously with other medications, and supplements are not regulated for purity or dose. In short, st. john's wort is best avoided during pregnancy when you follow the guidance below.

Why this is the guidance

Almost any medication you take can cross the placenta, so the question is never just “does it work” but “is the benefit worth any possible effect on the baby at this stage.” Many common drugs have safer pregnancy-friendly alternatives, and the safest choice can change by trimester.

Safer alternatives

St. John's Wort isn't recommended in pregnancy, but you rarely have to just tough it out — there's usually a pregnancy-safe alternative for the same problem. Don't start or stop anything important on your own: ask your provider or pharmacist for the safe swap before you need it.

What about breastfeeding?

Pregnancy and breastfeeding aren't the same — some things limited in pregnancy are perfectly fine once you're nursing, and occasionally the reverse. For st. john's wort while breastfeeding, check with your provider, since the answer can differ from the pregnancy guidance above.

The bottom line

St. John's Wort: best avoided in pregnancy. When in doubt, choose a safer alternative and ask your provider. This page is general education, not medical advice — your provider knows your history and is the final word for your pregnancy.

Frequently asked

Is st. john's wort safe during pregnancy?

It’s best avoided during pregnancy. St. John's Wort should be avoided in pregnancy because its safety is not established, it can interact dangerously with other medications, and supplements are not regulated for purity or dose. If you need an option, ask your provider for a pregnancy-safe alternative.

What can I take instead of st. john's wort?

Ask your provider for a pregnancy-safe alternative that fits your situation — there’s usually a good option, and they can match it to your history.

Is st. john's wort safe while breastfeeding?

Breastfeeding is often a different and more reassuring picture than pregnancy — some medications limited in pregnancy pass only in tiny amounts into breast milk. Check with your provider or pharmacist about st. john's wort for your situation and use standard dosing.