Enfamil Enspire Optimum vs ByHeart Whole Nutrition

Head-to-head in best baby formula, scored on our six-axis safety-first system.

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Our pick
Enfamil Enspire Optimum

Enfamil Enspire Optimum

8.3/10$42–$45/can
ByHeart Whole Nutrition

ByHeart Whole Nutrition

8.3/10$38–$40/can

Our verdict

Enfamil Enspire Optimum takes it on our safety-first score (8.3 vs 8.3), helped most by lactoferrin + mfgm. It’s close, though — the two are evenly matched, so let the price and the axis breakdown below decide.

Who wins each category

9.0Safety9.0
8.4Ease of use8.4
6.8Value7.0
8.4Durability8.4
8.6Comfort8.6
9.0Features8.6
Enfamil Enspire Optimum

Enfamil Enspire Optimum

$42–$45/can

ByHeart Whole Nutrition

ByHeart Whole Nutrition

$38–$40/can

Safety
9.0
9.0
Ease of use
8.4
8.4
Value
6.8
7.0
Durability
8.4
8.4
Comfort
8.6
8.6
Features
9.0
8.6

Want more options? See our full ranking of best baby formula.